Biochemistry

    

Successful Substitution of Prednisone by Saccharomyces Cerevisiae in Immune Thrombocytopenic Purpura: First Documented Case of Beta-Glucan-Mediated Immunomodulation Via Galt Pathway

Authors: Douglas Corrêa Cavasso

Background: Immune Thrombocytopenic Purpura (ITP) conventional treatment with corticosteroids presents significant adverse effects. This study documents the first case of successful corticosteroid substitution by S. cerevisiae in ITP, achieving 127,000 platelets/mm3 (24.5% superior to prednisone peak) through gut-associated lymphoid tissue (GALT) modulation.RESUMO EM PORTUGUÊS: Relato do primeiro caso documentado de substituição de prednisona por Saccharomyces cerevisiae na PTI, alcançando 127.000 plaquetas/mm3 via modulação do GALT, com estabilidade leucocitária e ausência de efeitos colaterais.

Comments: 13 Pages. Case report in English and Portuguese. Independent research documented at Hospital Erasto Gaertner.

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Submission history

[v1] 2026-01-26 22:53:29

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