This paper proposes a unified framework in which biology and physics are continuous manifestations of a single evolving causal web governed by two fundamental organizing principles: locality and relativity of local causalities. Local causal interactions constitute the elementary currency of change within this dynamic web. Persistence (memory) and stability emerge as relatively stable local interactions embedded in an ever-changing network. Apparent top-down or bottom-up causation does not represent a distinct causal category but arises from the accumulated history of local interactions. Reconceptualizing biology as a causal network in which natural selection shows as an emergent effect allows us to view the physical world as a seamless continuation of the same web operating acrossdifferent boundaries. Mass, forces, and motion are reinterpreted as manifestations and flows of causality governed by the same principles of locality, relationality, and historical embedding. In this framework, relativity is not primarily a theory of inertial frames or the measurement of clocks and rods, but a description of how local causality is dynamically organized and reassigned through relative motion within the network.The quantum domain represents a further extension of this evolving causal web. Experimental choices and measurement outcomes are co-determined by the web’s historical structure, eliminating the need for genuine nonlocality to explain quantum correlations. The universe is thus neither a sterile clockwork governed by eternal Platonic laws nor a collection of disconnected parts; it is a single, interconnected, evolving web.