Beyond the standard model, the DUO5 theory analyzes 72 puzzles (§2) to find their common point. With the constraint of avoiding any determinism, relative to an act of "creation", the analysis leads to the cause of the existence of the universe via the inertial paradox. By iteration, the precise link between the measurement of "effects" and their common "cause" is shown. It is shown that, like John Wheeler's theory, there is a common particle for particles and space-time. The analysis reveals: 1) that the physical structure of space-time is woven of dipolar oscillators, at the subquantum, non-local scale; 2) the cause of the instability of the local "creation" of matter; 3) that the notion of antimatter is an artifact relating to the non causal separation specific to locality; 4) the link between the stability of matter and the causal separation of primordial inflation; 5) the physical cause of inflation; 6) the original particle of the "preon" type, justified here, is named B.O.D.Y.S. (Subquantum Yin Yang Dipole Oscillator Boson). The iterative method between "cause" and "effects" allows to avoid the pitfall of self-reference and incompleteness of mathematical models, denounced by Gödel [3]. It is shown that the geometric aspect of the curvature of space-time, is only an "effect" of the "cause" relative to the physical coupling between the elements of matter and the B.O.D.Y.S structuring space-time. The study shows that the traces of the inertial paradox are present at all scales. This inertial paradox, constrains a state of permanent universe (without mass-spacetime continuum), matrix of the state of expanding and provisional universe. The study shows, that at the quantum scale, the notion of inertia m is inseparable from its spatial amplitude ℓ, forming a non-scalar moment of inertia: χ = m.ℓ. It is shown that it is the cause of the Heisenberg uncertainty. This entity is materialized by each of the two poles of the stochastic dipolar oscillator B.O.D.Y.S, whose existence is a solution to the inertial paradox.