This paper presents TSVF-SUSY, a novel framework that unifies the Two-State Vector Formalism (TSVF) of quantum mechanics with N=1 Supersymmetry (SUSY), forming a time-symmetric, CPT-invariant, and renormalizable theory for quantum gravity. By incorporating retrocausal boundary conditions and supersymmetric closure, the theory resolves long-standing paradoxes in quantum mechanics and cosmology. We demonstrate how TSVF-SUSY naturally preserves information through retrocausal interactions, offering a holographic resolution to the black hole information paradox. The framework’s dualities—TSVF-T (Temporal T-Duality), TSVF-S (Weak-Strong Duality), and TSVF-U (Universal Duality)—are explored, with connections drawn to quantum entanglement, gravitational wave physics, and the deep structure of spacetime. Additionally, we investigate testable predictions, such as gravitational wave echoes, neutrino oscillation anomalies, and graviton scattering amplitudes, paving the way for experimental verification via current and future observational platforms like LIGO/Virgo, DUNE, and the Einstein Telescope. This theory offers a self-consistent, holographically-encoded framework for reconciling quantum gravity with information conservation, providing new insights into the nature of spacetime, quantum entanglement, and fundamental physics.