As it is known, the Lorentz Transformation is the transformation of coordinates between reference systems in uniform relative motion that is at the basis of the Theory of Relativity. But what is its physical meaning? What do the variables obtained by applying this mathematical transformation represent, physically? The interpretation that currently prevails in the context of contemporary physics is that these variables represent the physical space and time coordinates of a given event for a reference system in uniform and rectilinear motion with respect to another one. According to this interpretation, two events that are simultaneous for a given reference system are not simultaneous for another reference system that is in motion with respect to the first one, the so-called "relativity of simultaneity", and therefore time and space are no longer absolute, invariant in the passage from one reference system to another, but become relative, resulting dependent from the state of motion ofthe system being considered.