In this book I update the 1890s Theosophist and 1970s New Age attempts to fuse spiritualism with modern science. The main inspiration for Astrological Darwinism comes from the esoteric works of the philosopher Bergson and the Egyptologist Schwaller de Lubicz. In this book I elaborate the intuition that the Astrological Great Year is fundamentally a Cycle of Life in the evolution of humanity. The core of this idea is that a cyclic manifestation of Bergsons ‘élan vital’ can be projected onto the Zodiac of Denderah. A cyclic version of Bergson’s ‘Creative Evolution’ results and will be applied to human evolution of the last hundred thousand years. Schwaller de Lubicz suggested that the Zodiac of Denderah depicted the Pharaonic Egyptians’ knowledge of three such cycles, thus dating back to the very paleo-anthropological origin of human symbolism, some seventy eight thousand years ago.According to the sociologist Weber, our era can be characterised by a steady process of ‘Disenchantment’, of progressive objectification and technological advancement. In playback we would see a process of reversed-Weberian Enchantment. This playback is our prophesied future. Our present-day linear conception of history and evolution is thus replaced by a cyclic view, following the timeline of the Great Year of Astrology. Disenchantment will continue and peak at the Age of Aquarius, after which re-enchantment will set in and peak again at the future Age of Leo, fourteen thousand years from now. I identify this ‘peak magic’ as ‘peak creative evolution’ in line with Bergson’s neovitalism.Philosophically, Astrological Darwinism centres around two axioms. The first is the quantum axiom of `chosen wave function collapse' and its biological subset of `chosen mutations'. It is the Bersonian `élan vital' of the soul that makes the choices by quantum looking at the genes and thus acting as a metaphysical or vital `hidden variable' causing genetic mutations. The 'Goddess Principle' is a more appropriate name for this axiom, because the main active agents of this capacity are women during or around the Age of Leo. The second axiom is that the capacity of complex, multicellular life forms to apply this `chosen mutations' is cyclic, following the 26.000 year precession of the equinox. I expect this second axiom to be verified by a future quantum-gravity-biology, which might be developed in the next hundred years or so.Astrological Darwinism is a metaphysical narrative with implications for evolutionary biology, history and trans-humanism. In this book, the last six Great Years are reconstructed, going back 140 thousand years, thus producing a new Grand Narrative of human evolution.