The study of memory is one of the most intensively studied areas of neuroscience. Many models of memory have been proposed. However, few of the previous models of long-term memory have proposed very detailed mechanisms of memory creation, storage and retrieval. Furthermore, very few models propose a role for astrocytes in long-term memory. To bridge these gaps in knowledge, the author has proposed a comprehensive theoretical memory molecule model of long-term memory whereby all types of memory are stored in a similar manner in memory molecules located in discrete memory modules. Each memory molecule can store one elementary unit of memory in binary form based on the conformation of the memory molecule. A novel memory read/write mechanism has been proposed to store and retrieve memories. The model emphasises the essential role of astrocytes in long-term potentiation; creating, supporting, and activating neural circuitry; and facilitating long-term memory. The model can provide possible explanations for the results of several memory studies, and the causes of some neurological conditions such as Alzheimer’s Disease.