Gingival recession, characterized by the apical migration of gingival tissue, leads to root exposure and subsequent complications such as sensitivity, root caries, and periodontal disease. Current treatment options, including tissue grafts and regenerative therapies, are limited by their invasiveness and inconsistent outcomes. This study proposes a silk fibroin scaffold infused with three growth factors (EGF, FGF, VEGF) and three adhesive proteins (laminin, fibronectin, osteonectin) to enhance gingival cell proliferation, attachment, and integration with the alveolar bone. The scaffold aims to promote natural gingival regeneration while providing structural support. The development process, efficacy testing, and expected clinical application of this novel gingival regeneration scaffold are outlined. This approach, if successful, could offer a safer, non-invasive, and cost-effective solution for treating gingival recession.