This article explores the possible place, time, and scale of the Great Flood as recorded in the Bible. The results of this paper conclude that the existence of the Bible-recorded Flood is highly likely. The time was about 4,500 years ago in the plains of Mesopotamia. The flood was caused by the failure of a massive glacial lake dam in the desert region of southern Afghanistan that existed after the end of the last glacial period. Due to the dam failure in the western part of the glacier lake in the Tarim Basin of the western plateau of China, the water of the glacier lake continues to flow into the glacier lake in southern Afghanistan. When the glacial lake in southern Afghanistan overflowed, it continued to wash away the glacial lake dikes made of soft soil, and eventually caused the dam failure of the glacial lake in southern Afghanistan, resulting in huge floods and mudslides. After the energy of these floods and mudslides was released in a concentrated manner at the outlet of the Persian Gulf, part of the energy produced a huge Seiche standing wave phenomenon in the closed interior of the Persian Gulf, which caused a tsunami in the Mesopotamian Plain that lasted for about seven days, up to one or two hundred meters, and then soaked the Mesopotamian Plain in the 50 meters deep flood for dozens of days.