Measurements of the parameters of the observed Universe is a very difficult task and does not give the necessary accuracy. A mathematical method for obtaining the parameters of the Universe has been found. The method is based on the revealed relationship between the parameters of the Universe and the dependence of their values on the fundamental physical constants. New large numbers on the previously unknown scales 10^140, 10^160 and 10^180 were derived. The new large numbers allowed us to obtain new cosmological equations linking the parameters of the Universe with fundamental physical constants. The number of new cosmological equations and their constituent parmeters was sufficient to unite the equations into a system of cosmological equations. This made it possible to form a system of algebraic equations containing all parameters of the Universe. As a result, it became possible to obtain the parameters of the Universe by mathematical method. The parameters of the Universe are the roots of the system of algebraic equations of the Universe. The theory based on the law of scaling of large numbers allows us to obtain the parameters of the observed Universe with an accuracy close to the accuracy of the Newtonian constant of gravitation G. The results obtained show that the Universe is tuned with high mathematical accuracy.