The connection between the parameters of the Universe and fundamental physical constants is disclosed. It is shown that three constants G, c, Ʌ are sufficient to obtain all the parameters of the Universe. The parameters of the Universe and the parameters of the electron are mathematically precisely related to each other by scale transformations. The scaling factors are formed by the large Weyl number and the fine structure constant "alpha". The scaling factors are derived from the law of scaling of large numbers. The appearance of the fine structure constant "alpha" and electron constants in the cosmological equations is evidence of the fundamental connection between microphysics and cosmology. The disclosure of the origin of the parameters of the Universe from the fundamental physical constants of the electron provides new possibilities. By studying the electron, one can unravel the mysteries of the Universe.