This paper extends the ideas presented in our previous work, "Introduction to the Theory of Time Frames: 1) Time Flow."Central to this theory is the notion that time can flow at different rates in different regions of space, leading to a reevaluation of time dilation.As a logical consequence of observing inertial reference frames within the context of different time flows, the need to introduce the concept of "time frames" became apparent. The concept of time frames includes inertial frames of reference within a region of space with a definite flow of time.To compare physical phenomena between time frames with distinct time flows, we introduced a set of relations or formulas referred to as "time transformations." These time transformations enable observers to translate and relate measurements made in one time frame to those made in another time frame with a different time flow.Within the framework of time transformations, several novel concepts were additionally introduced. These concepts include the "time flow coefficient (p)," the "time flow ratio ()," and the "time deceleration coefficient (δ)," which are necessary for furthering our understanding of the relationship between different time frames with varying flows of time.It should be noted that the theory of time frames departs from Einstein's established theories of relativity, rejecting the concept of four-dimensional spacetime and describing a universe with three spatial dimensions and time as a separate, variable entity.This unconventional viewpoint aims to open up new perspectives on the underlying nature of time and its role in shaping the universe.With these advancements, we have laid a solid foundation for the theory of time frames and established a robust framework for its ongoing exploration and refinement.