Type 2 diabetes, often referred to as T2D, is a widespread health condition. This study focuses on the specific genetic variation in a single nucleotide poly- morphism (SNP) rs7903146 in the gene TCF7L2 and its potential association with T2D. We examined DNA samples from Bangladeshi individuals to see whether the genetic variant rs7903146 is associated with T2D in this community. We discovered that the CC variant of rs7903146 was extremely prevalent, appearing in all of the samples from people without T2D and in the majority of the samples from people with T2D out of the 38 sequences they looked at (16 from people without T2D and 22 from people with T2D). In a tiny proportion of T2D patients, there was also a less prevalent variant called CT. Surprisingly, the Bangladeshi population in this study did not show a clear association be- tween rs7903146 and T2D. This counters what several earlier investigations have found. This opens the door for more future research to completely comprehend the genetic and environmental causes of T2D to build preventative treatments for this quickly increasing global health problem.