This paper speaks of the measurement of the CMB from the point of view of a non-standard model named 4-Sphere.The CMB is the result of the expansion of the Radiation Era relic. The consequence of this is in its homogeneity and isotropy even among distant points of the Universe. We can find small difference of its property, say CMB anisotropies [1], for various reasons. The most important concerns the discontinuities in the primordial plasma concentration, with production of gravity and pressure gradients of local character coming from the Inflationary Era. Physicists think these are the origin of galaxies and galaxy clusters.Given the extreme complexity of the matter we will not adapt the Cosmological Perturbation of ΛCDM to 4-Sphere, but we will limit ourselves to a qualitative description of radiation interacting with the plasma, with pressure gradients proceeding in one isochoric scenario. We will show that all this is compatible with the "bottom-up" growth of the galactic structures we observe now. A snapshot at Last Scattering of this situation is transmitted to us through the anisotropy of the CMB. We will see how the CMB dipole, measured by an observer in peculiar motion, is coherent with the 4-Sphere geometry. But the discussion is mainly about the temperature anisotropy due to cosmological perturbations. It follows that, with a directional antenna, what we measure is the interference of the overlapping radiation from two opposite directions: Maybe it could arise from the same cosmological perturbation. From that, a way to recognize the existence of the fourth dimension of space is proposed, as a verification of the 4-Sphere model.Somewhere in the discussion there are questions and answers to ChatGPT, our Artificial Intelligence (see https://openai.com/), to know his thought and fill the gap in knowledge.