The subject of the study was the validity of claims of excessive mathematicalization of physics. To solve the problem, the individuality and interrelation of constituent components of Nature is accepted as an axiom. The description of individuality and interrelation, on the basis of positive and negative feedback is offered. Positive feedback describes the polar interaction. Negative feedback describes the mutual dependence of the components. The appearance of symbiosis is shown, as well as the evolution of the dual connection. Restrictions of the system's physical minimum and preservation of its functionality are considered. The practical impossibility of creating stable particles from unstable ones is postulated. An explanation of constants and existence of mathematical limitations in describing the reality is obtained. Necessity of restrictions of mathematics application is shown, at the description of physical processes. The results of restrictions on the application of mathematics in physics are considered.Key words: physical sense, image, form, abstraction, efficiency, duality, mutual dependence, functionality, uroboros, emptiness.