Experimental evidence is presented showing that a rapidly rotating gyroscope experiences a lift force opposing gravity. The theory is derived by considering the centrifugal forces (with the Earth’s center as the origin) that act on a cylindrically symmetric, rapidly rotating rigid body. Under normal circumstances, this effect is completely negligible compared to other forces acting on the gyroscope. Therefore, this experiment was designed for a rapidly spinning mechanical gyroscope by placing it on a sensitive scale in a vacuum chamber. Experimental methods and data analysis methods are also presented. The data shows that the effect is much larger than anticipated by the theory, and that the effect seems to be enhanced through interaction with electromagnetic (EM) fields. Our conclusion is that the data indicated that our theory is partially correct, but incomplete, and likely to be missing at least one effect related to electromagnetism.