Biochemistry

    

Sars-Cov-2 and Most Respiratory Viruses Replicate More Efficiently Below the Normal Body Temperature of Their Hosts

Authors: Patrick D. S. Stewart, Julia L. Bach

In April 2021 we published a review of the factors underlying the seasonality and pathogenicity of respiratory viruses [1]. We showed that many respiratory viruses possess natural thermal sensitivity, meaning they replicate faster at temperatures below their hosts’ normal body temperature, allowing them to confine themselves to the upper airways. This tropism can give them at least two important advantages: (1) they are well-placed to be transmitted; and (2) they are less likely to immobilize their hosts, increasing transmission.

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[v1] 2022-04-28 20:23:30

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