Psychophysical nature of the epistemology of the Clinical Medicine (ECM) actually used spontaneously in daily practice by each doctor is discussed in this treatise. ECM spontaneously functions nowadays as a basis of each doctor's clinical thinking (intellection). The modern official science distinguishes scientific and practical parts of Medicine considering Clinical Medicine as area of practical application of scientific Medicine or Biomedicine. Thus, modern official medicine ignores ECM, which works within physician's practice, and thereby official medicine replaces ECM with the natural-science epistemology used in Biology and Physics. However Medicine is an independent self-contained practical science. This definition Avicenna justified about 1000 years ago and asserted that we cannot be considering Medicine as practical branch of natural sciences. The tradition to distinguish practical and scientific parts of Medicine has arisen during the European Renaissance, and it became stronger during Modern history, in process of Biomedicine formation. Now this tradition meets many difficulties. As well as in Ancient time, the modern doctors' clinical thinking is based on a principle of the psychophysical non-duality of human nature. Basic scheme of application of this principle in clinical thinking within the course of the doctoring process of any patient is described briefly here.