Pollution is a significant problem that Egypt faces and air pollution is its most dangerous type of pollution. Gases like carbon monoxide and nitrogen oxides increased concentration affects health which is mostly produced by combustion reactions in car fumes or factories. Also, it causes diseases like asthma, Alzheimer's, even cancer and also affect the economy by affecting crops growth and decreasing it. The negative effect of air pollution on plants can be used as a bioindicator of pollutants concentration by noticing the growth of pollution-sensitive plants as lichens in polluted areas; the more its growth is affected, the more the pollutants are concentrated. One of the most dangerous pollutants is nitrogen oxides; most of the pollutant's concentration comes from traffic emissions. Nitrogen oxides can cause severe health issues as irritation of the respiratory tract, and it can reduce immunity to lung infections. Also, carbon monoxide is a hazardous pollutant that may cause loss of balance, vision problems, memory problems, loss of consciousness and eventually, death. The increased concentration of pollutants and greenhouse gases like chlorofluorocarbon and nitrogen oxides damages the ozone layer critically. It threatens human health as the ozone layer is the earth's shield against harmful rays coming from space as ultraviolet rays, for example, exposure to UV rays causes skin cancer premature ageing and other skin damage eye damage and Immune system weakness. Polluting gases are mostly produced by combustion reactions providing both heat and additional residue in the form of pollution as mentioned earlier, thermodynamics rules these reactions and expresses them. The first and second laws of thermodynamics discuss these reactions and help us get a better view of the problem which can help scientist find better and more efficient solutions in the future by understanding the roots of the problem.