Invasive measurement of blood glucose is not appropriate for everyone, particularly the patients with leukemia. Here, we demonstrate how the blood glucose can be non-invasively monitored over a prolonged period in the absence of any expensive equipment. Method: A portable and non-invasive glucose sensor capable of monitoring blood glucose in real-time has been successfully constructed and tested in the absence of any vector network analyzer. Using vacuum suction, the sensor head of the proposed non-invasive glucose sensor forms a whispering gallery resonator out of a skin tissue on an arm during the measurement process. The architecture of the proposed glucose sensor is equipped with standard components, including a WIFI transmitter, an RSSI sensor and a microcontroller based computer display. Results: Using the proposed glucose sensor, a healthy volunteer has been his blood glucose levels monitored over 72 minutes after consuming a loaf of bread and a cup of cow milk. The measured blood glucose rose shortly after the meal until it peaked at 40 minutes and finally fell to the initial value at around 72 minutes. Conclusion: The overall results were in general consistent with the expected results. The proposed glucose sensor is expected to be instrumental for the individuals who dislike the traditional lancets.