Different from the homogenous systems, a Smarandache system is a contra-dictory system in which an axiom behaves in at least two different ways within the same system, i.e., validated and invalided, or only invalided but in multiple distinct ways. Such systems widely exist in the world. In this report, we discuss such a kind of Smarandache sys-tem, i.e., non-solvable equation systems, such as those of non-solvable algebraic equations,non-solvable ordinary differential equations and non-solvable partial differential equations by topological graphs, classify these systems and characterize their global behaviors, partic-ularly, the sum-stability and prod-stability of such equations. Applications of such systems to other sciences, such as those of controlling of infectious diseases, interaction fields and flows in network are also included in this report.