It is shown, that the Earth biosphere main parameters, such as the alive matter total mass, the DNA and peptides length, are connected with the observed Universe parameters. In particular, the length of the integral genome DNA of the Earth biosphere is equal to the Hubble radius. The consideration of humanity as the biosphere matter especial part provides us to value the human mass limit and extremal quantity; the obtained results coincide with the ones, calculated by the demography specialists. The obtained relations are explained by the author conception of the synergistical evolutioning Universe, where the nonequilibrium structures, including the alive ones, are created under the action of the observed energy forms as well as of the dark energy. The connection between the biosphere and Universe parameters provides us to extend the Anthropic principle notion as well as the observer conception because the biosphere is an adaptation tracing system, which adjusts itself under the Universe evolution to be the one unit with it. Keywords: biosphere, cosmological parameters, Hubble radius, DNA length, humanity mass, Earth biosphere mass, Universe mass, Hubble radius, P. Dirac Big Numbers, fine structure constant, synergetical Universe, biospheres number in the Universe.